Getting to Know the Compound

Often labeled as α-bromopropionic acid or DL-2-bromopropionic acid (also sold as 2-Bromine Propionic or RARECHEM AL BO 1266), this halogenated carboxylic acid (CAS 598-72-1) typically appears as a clear, pale yellow to colorless liquid. What makes it stand out? Its reactive α-bromo group serves as a versatile handle for precision chemistry, positioning it as a go-to precursor for pharmaceuticals and agrochemicals.

Key Characteristics & Handling

With a molar mass of 152.97 g/mol, 2-bromopropionic acid (C₃H₅BrO₂) packs a density of 1.7 g/mL at room temperature. It melts around 25.7°C and boils near 203°C. Lab technicians note its complete water solubility—a practical trait that simplifies blending into both aqueous and organic reaction mixtures. Safety-wise, the 100°C (212°F) flash point calls for standard precautions. But the real star is that α-bromo group, readily participating in nucleophilic swaps, eliminations, and radical reactions.

Agrochemical Impact

In crop science, this compound proves particularly valuable. It’s a key starting point for herbicides like quizalofop-ethyl and metolachlor, where its reactivity efficiently builds oxazolone or thiazolone cores. Field tests show that leveraging the DL-2-bromopropionic acid form streamlines production, cutting down unwanted byproducts while boosting yields in grass-specific weed control agents.

Drug Discovery & Synthesis

Pharmaceutical teams frequently turn to 2-bromopropionic acid (sometimes listed as 2-bromopropanoic acid solution) when crafting alanine derivatives or chiral auxiliaries. Its DL-form allows clean resolution into single (2R)- or (2S)- enantiomers—critical for asymmetric syntheses of complex drug molecules. The acid’s reliability in amide-bond formation and catalyzed couplings makes it a lab staple for assembling bioactive heterocycles.

Why It Matters

2-Bromopropionic acid (CAS 598-72-1) delivers a rare blend: water compatibility, manageable phase transitions, and that highly reactive α-bromo site. Whether you’re developing precision herbicides or stereochemically pure APIs, this multipurpose chemical building block offers scalable solutions. For formulation support, bulk sourcing, or process optimization, our technical team provides tailored guidance—just reach out.