Opening Insights

Clear. Colorless. Highly reactive. Isobutyronitrile (often called 2-Cyanopropane or isopropyl cyanide) packs serious versatility into its modest C₄H₇N structure (molar mass: 69.11 g/mol). This low-boiling nitrile (CAS 78-82-0) serves as a linchpin intermediate for manufacturers – particularly those crafting advanced pesticides and performance polymers. What makes it so valuable? Industry experts point to its favorable volatility and almost chameleon-like reactivity.

Core Characteristics

Handling this material requires attention to its physical profile:
- Density: 0.770 g/mL at 20°C
- Phase Behavior: Melts at –72°C, boils between 107–108°C
- Safety Note: Flash point just below 4°C (39°F) – always store in designated flammables areas away from ignition sources
- Appearance: Typically a clear, colorless liquid (may show light yellow tint)

Its branched structure and that terminal nitrile group act like a chemical Swiss Army knife. Labs leverage this for nucleophilic substitutions, condensations, and cyclizations. Interestingly, the low melting/boiling points make it surprisingly forgiving in continuous-flow manufacturing – a fact process engineers appreciate.

Where Chemistry Meets Application

Agrochemical Dominance:

Field after field, isobutyronitrile proves indispensable in synthesizing organophosphorus insecticides. It’s the unsung hero behind:
- Diazinon:Where it builds the critical isobutyramidine intermediate
- 2-Isopropyl-4-methyl-6-hydroxypyrimidine:The pivotal precursor in diazinon’s production pathway
- Next-gen crop protection agents targeting evolving pest resistance

Beyond the Fields:

Pharma labs exploit the nitrile group, transforming it into amines, carboxylic acids, and complex heterocycles. Meanwhile, polymer scientists deploy it as a strategic modifier in acrylic resin production. Here’s why: it co-polymerizes smoothly with radical starters and functional monomers, enhancing durability in coatings, adhesives, and engineering plastics. Case studies suggest resins modified with isobutyronitrile withstand harsh solvents 15-20% longer.

Why Manufacturers Keep Choosing It

Simply put, isobutyronitrile (CAS 78-82-0) delivers. Its blend of reactivity, manageable physical properties, and scalability makes it a go-to for:
1. High-volume agrochemical synthesis (especially diazinon derivatives)
2. Precision pharmaceutical building blocks
3. Performance polymer enhancement

Consequently, procurement teams consistently rank it among the top nitrile intermediates for reliable supply chain integration.

Final Notes

From insecticide formulations to the adhesive bonding your smartphone, isobutyronitrile’s fingerprints are everywhere. For technical specs, sourcing options, or formulation troubleshooting, our specialists offer real-world guidance – just reach out.