This unassuming quaternary ammonium salt punches far above its weight class. While its chemical structure seems straightforward, choline chloride quietly powers vital processes across veterinary science, crop cultivation, clinical practice, and biotechnology. Our comprehensive profile transforms technical data into actionable insights—perfect for professionals who value precision paired with readability.

Core Identity

Systematic Name: Choline chloride

Key Aliases:                                                                                                                                       BE HOEtN1,1,1Cl (Chemical notation)                                                                                                                 Cholinii chloridum (Pharmacopeial designation)                                                                                                         2-Hydroxyethyl trimethylammonium chloride (IUPAC name)                                                                        FCC Grade Choline chloride (Food-chemical specification)

CAS Registry: 67-48-1

Molecular Blueprint: C₅H₁₄ClNO

Mass Profile: 139.62 g/mol

Physical & Chemical Profile

Density: Approximately 1.0238 g/cm³

Thermal Threshold: Decomposes at 302–305°C

Morphology: Sticky crystalline aggregates*

Color Profile: Bright white

Fun fact: Those stubborn clumps aren't poor storage—they're evidence of extreme hygroscopicity. This affinity for moisture explains why fluffy powders remain elusive. Store under airtight conditions at ambient temperature to prevent caking.

Solubility & Stability

Versatile Applications

Animal Nutrition Powerhouse

Feed mills worldwide prioritize this additive—and for good reason. Beyond preventing costly fatty liver syndrome, it turbocharges metabolic efficiency：
Metabolic Enhancement:Optimizes methionine utilization 
Livestock Vitality:Boosts immunity + fetal/juvenile development 
Production Metrics:Raises egg yield by 12-18%, improves litter sizes 
Physical Integrity:Strengthens bone density and fur quality   

Practical Implementation:

Standard inclusion: 1–2g/kg complete feed

Dominates Japanese agriculture—98% used in poultry, swine, and aquaculture operations

Photosynthesis Booster for Crops

Field trials confirm significant yield increases (5-22% crop-dependent) through two mechanisms:

Primary Action Pathways:

Chlorophyll synthesis amplifier

Environmental stress mitigator

Key Beneficiaries:

Staple crops: Corn, potatoes, sugarcane

Commercial species: Cotton, tobacco, grapes

Vegetables: Radish, onion clusters, leafy greens

Biomedical Deployments

Classified within vitamin B-complex nutrients, its clinical applications include:

Hepatic Health: Frontline agent against fatty infiltration and cirrhosis progression

Blood Support: Adjuvant therapy for pernicious anemia

Mechanism: Functions as a lipotropic compound—shuttles fat away from liver tissue

Food Science & Consumer Health

As a human nutritional supplement:

Cost-effective source (~85% pure choline)

Supports brain function and lipid metabolism

GRAS-listed for functional foods and beverages

Specialized Industrial Roles

Serves critical functions in:

Cell culture media formulations

Multivitamin compounding

API synthesis

Custom premixes (integrated micronutrient blends)

Manufacturing Insights

Commercial 50% powder production follows precise protocol:

Prepare silica/carrier base with calibrated particle distribution

Gradually introduce aqueous choline chloride via metered dripping

Homogenize under controlled humidity

Fluid-bed dry to <1% moisture content

Advanced variants incorporate stabilizers, vitamins, or cofactors during granulation.

Strategic Value Proposition

Why does this compound dominate global supply chains? Three compelling reasons:

Biological Leverage: Delivers methyl groups essential for cellular operations

Economic Efficiency: Highest choline content per dollar

Compatibility: Blends seamlessly across biological systems

From stabilizing cattle feed to boosting vaccine production yields, choline chloride remains the quiet workhorse of industrial biochemistry. Its chemical humility masks irreplaceable functionality—a testament to the power of molecular simplicity.