Introduction:

2-Bromopropionic acid, known by various synonyms and identified by the CAS number 598-72-1, is a crucial component in organic synthesis and pharmaceutical intermediates. This article delves into its properties, diverse applications, and the necessary handling procedures to ensure safe utilization across various industries.

Properties:

With a chemical formula of C3H5BrO2 and a molar mass of 152.97 g/mol, 2-bromopropionic acid manifests as a clear colorless to yellow liquid with a density of approximately 1.7 g/mL at 25°C. Its melting point stands at 25.7°C, while its boiling point reaches 203°C. These characteristics render it suitable for a range of organic synthesis and pharmaceutical applications.

Applications:

Derived from the bromination of propionic acid, 2-bromopropionic acid serves as a critical organic intermediate. It is instrumental in the synthesis of various organic materials, pharmaceuticals, herbicides, and fungicides. Notably, it contributes to the production of herbicides like quizaloxazole, oxazolaproxyl, and thiazolaproxyl, as well as fungicides such as metalaxyl and benzoxyl.

Safety and Handling:

Prudent storage and transportation practices are essential for 2-bromopropionic acid. Ventilated warehouses with temperature control capabilities are recommended, with storage separate from oxidants, alkalis, and food raw materials to prevent potential reactions. When handling this compound, appropriate protective equipment should be worn to avoid direct skin contact, eye exposure, or inhalation of vapors.

Conclusion:

In summary, 2-bromopropionic acid holds significant importance in organic synthesis and pharmaceutical industries, owing to its diverse applications. Adherence to proper handling procedures and understanding of its properties are paramount for ensuring safe utilization in chemical processes. By following recommended storage and handling protocols, chemists and researchers can effectively harness the potential of 2-bromopropionic acid while upholding safety standards in the workplace.