Introduction:

Ethyl acetoacetate (CAS number: 141-97-9), also known as EAA or Ethyl 3-oxobutanoate, is a versatile organic compound widely used in synthetic chemistry and various industries. It serves as a crucial intermediate in the production of a variety of chemicals and plays an essential role in many industrial applications.

Chemical Profile:

       Molecular Formula: C6H10O3

       Molar Mass: 130.14 g/mol

       Density: 1.029 g/mL at 20°C

       Melting Point: -43°C

       Boiling Point: 181°C

       Flash Point: 185°F

       Water Solubility: 116 g/L at 20°C

       Appearance: Transparent liquid

       Solubility: Soluble in water and many organic solvents

Storage Conditions:

Store Ethyl acetoacetate in a cool, ventilated area below +30°C. Ensure proper fireproof measures are in place due to its flammable nature.

Applications:

Organic Synthesis:

Ethyl acetoacetate is a key intermediate for the synthesis of heterocyclic compounds, including pyridine, pyrrole, pyrazolone, pyrimidine, purine, and cyclic lactones.

Pharmaceuticals:

t is used in the synthesis of drugs such as aminopyrine and vitamin B, contributing to the development of essential pharmaceutical compounds.

Pesticides:

In the agrochemical industry, Ethyl acetoacetate is employed to produce intermediates for various insecticides (organophosphorus and carbamate), fungicides, and herbicides.

Flavor and Fragrance:

It serves as a food flavoring agent, particularly in the creation of apple and other fruit flavors, adding to its value in the food and beverage industry.

Dyes and Pigments:

Ethyl acetoacetate is used in the preparation of azo yellow dyes and other colorants, contributing to the dye manufacturing industry.

Solvent and Reagent: 

Functions as a solvent and a reagent in various chemical processes, including the detection of thallium, calcium oxide, calcium hydroxide, and copper.

Gas Chromatography:

Used as a stationary phase in gas chromatography, it aids in analytical testing and research applications.

Complexation Indicator:

Employed in determining high iron levels, making it useful in chemical analysis and environmental monitoring.

Conclusion:

Ethyl acetoacetate is a highly versatile compound with a broad range of applications in pharmaceuticals, agriculture, food flavoring, and chemical manufacturing. Its ability to serve as a building block for various organic compounds, along with its solubility properties, makes it an indispensable tool in both research and industrial processes.