Introduction

Guanidine Hydrochloride (GuHCl), with the chemical formula CH6N3Cl, is a white crystalline compound widely used in pharmaceutical manufacturing and industrial applications. This versatile chemical serves as a crucial intermediate in various synthetic processes and holds significant importance in protein research.

Chemical Properties and Characteristics

Guanidine Hydrochloride(CAS:50-01-1) presents as a white to slightly yellowish solid with a molecular mass of 95.53 g/mol. It demonstrates excellent solubility in water (2280 g/L at 20°C) and ethanol, forming neutral solutions. The compound has a melting point range of 180-185°C and boils at 172.8°C under standard pressure (760 mmHg).

Physical Specifications

       Density: 1.18 g/mL at 25°C

       Flash Point: 58.3°C

       Vapor Pressure: 1.13 mmHg at 25°C

       Storage: Stable at room temperature

Industrial Applications

Pharmaceutical Synthesis

The compound serves as a vital intermediate in the production of several important pharmaceutical products, including:

       Sulfadiazine

       Sulfamethazine

       Folic acid derivatives

       Various pyrimidine-based compounds

Technical Applications

In addition to its pharmaceutical uses, Guanidine Hydrochloride finds applications in:

       Protein denaturation studies as a chaotropic agent

       Antistatic treatment of synthetic fibers

       Organic synthesis processes

       Pesticide manufacturing

       Dye production

Conclusion

Guanidine Hydrochloride remains an essential chemical compound in modern pharmaceutical and industrial processes. Its unique properties and versatile nature make it indispensable for various applications, from drug synthesis to technical manufacturing processes.